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Slide 1: Series of embryos with Hox-Exd binding sites successively mutated in a reporter gene
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Slide 6: Word jumble for the Mann lab
Slide 7: Stochastic flybow labeling of individual neuropil glia
Slide 8: Human towers of Catalonia by David Oliete
We study how the Hox family of transcription factors bind to the correct DNA sequences and regulate the correct target genes in vivo.
We are studying how the neural circuitry that is required for coordinated walking in adult flies is constructed during development, and how it functions in the adult.
A new collaborative paper with the Bussemaker lab (Rastogi et al) was just published in PNAS. In this paper, we describe a powerful new computational tool, NRLB, that uses round 1 SELEX-seq data for any transcription factor to model the relative affinities of all binding sites. Thus the name: No Read Left Behind.
See also the Zuckerman Institute's news article here.
Differing Strategies Despite Shared Lineages of Motor Neurons and Glia to Achieve Robust Development of an Adult Neuropil in Drosophila
Jonathan Enriquez, Laura Quintana Rio, Richard Blazeski, Stephanie Bellemin, Pierre Godement, Carol Mason, Richard S. Mann