Image Carousel with 12 slides
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Slide 1: Tarsal depressor MN dendrites
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Slide 2: Series of embryos with Hox-Exd binding sites successively mutated in a reporter gene
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Slide 7: Word jumble for the Mann lab
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Slide 8: Stochastic flybow labeling of individual neuropil glia
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Slide 9: Human towers of Catalonia by David Oliete
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Slide 10: A fly leg imaginal disc
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Slide 11: Four x-ray structures of AbdB-Exd bound to four different binding sites
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Slide 12: Single serotonergic neurons in the fly VNC
Active Research Projects
The Control of Transcription Factor Specificity and Activity
We study how transcription factors bind to the correct DNA sequences and regulate the correct target genes in vivo, with a focus on the Hox family of homeodomain proteins.
Motor Neuron Development and Circuitry
We are studying how the neural circuitry that is required for coordinated walking in adult flies is constructed during development, and how it functions in the adult.
Recent Publication
Dense and pleiotropic regulatory information in a developmental enhancer
News
Welcome Nadeera
The Mann lab welcomes new postdoc Nadeera Wickramasinghe, who just started this past week. Nadeera did her PhD at Mt. Sinai, NYC, in the laboratory of Dr. Nicole Dubois. Nadeera "met" and decided to come to the lab with only virtual information, so it was especially fun to meet her in person this week!
Ryan Loker successfully defends his thesis
There were many reasons to celebrate Ryan Loker's thesis defense yesterday. Not only was there a lively discussion with his committee (Stavros Lomvardas, Hynek Wichterle, Gary Struhl, Jeremy Dasen) but it was the first 'in person' thesis defense in more than a year.
Congratulations, Ryan, for an amazing job and for producing a beautiful body of work.
Ross Munce passes Qual exam, part 1
He survived Struhl, Hobert, and Lomvardas.
Photos
Neuropils of the Drosophila VNC
Dendrites and cell bodies of a pair of tarsal depressor motor neurons
Image from Manntastic event, June 14, 2019