Recent Publications

2021

An abx bx pbx/DfP2 four winged mutant. Photograph by Nicolas Gompel, University of Munich

Cell-type-specific Hox regulatory strategies orchestrate tissue identity

Ryan Loker
Jordyn Sanner
Richard S. Mann

Homothorax controls a binary Rhodopsin switch in Drosophila ocelli

Abhishek Kumar Mishra, Cornelia Fritsch, Roumen Voutev, Richard S Mann, Simon G Sprecher

Scarless engineering of the Drosophila genome near any site-specific integration site.

Siqian Feng
Shan Lu
Wesley B Grueber
Richard S Mann

2020

Types of changes to CRM activities after random mutagenesis

Dense and pleiotropic regulatory information in a developmental enhancer

Timothy Fuqua, Jeff Jordan, Maria Elize van Breugel, Aliaksandr Halavatyi, Christian Tischer, Peter Polidoro, Namiko Abe, Albert Tsai, Richard S. Mann, David L. Stern & Justin Crocker

A size principle for recruitment of Drosophila leg motor neurons

Azevedo AW
Dickinson ES
Gurung P
Venkatasubramanian L
Mann RS
Tuthill JC

Control of tissue morphogenesis by the HOX gene Ultrabithorax

Diaz-de-la-Loza MD
Loker R
Mann RS
Thompson BJ

2019

haltere imaginal disc with clones

A role for low affinity binding sites in fine tuning the levels of transcription

Rebecca K. Delker, Vikram Ranade, Ryan Loker, Roumen Voutev, Richard S. Mann

Low-Affinity Binding Sites and the Transcription Factor Specificity Paradox in Eukaryotes

Judith Kribelbauer
Chaitanya Rastogi
Harmen Bussemaker
Richard S. Mann

2018

2017

Using genome engineering to better understand animal development

Rebecca Delker & Richard S. Mann
Calculating electrostatic potentials in DNA grooves

Still thinking about electrostatic potentials

Tsu-Pei Chiu, Satyanarayan Rao, Richard S. Mann, Barry Honig, Remo Rohs

Bxb1 phage recombinase assists genome engineering in Drosophila melanogaster

Roumen Voutev
Richard S. Mann

2016

The Importance of Timing

Richard S. Mann
Clare Howard

To Be Specific or Not: The Critical Relationship Between Hox and TALE Proteins

Samir Merabet
Richard S. Mann

Streamlined scanning for enhancer elements in Drosophila melanogaster

Roumen Voutev
Richard S. Mann

2015

Building accurate sequence-to-affinity models from high-throughput in vitro protein-DNA binding data using FeatureREDUCE.

Todd Riley
A. Lazarovici
Richard S. Mann
Harmen Bussemaker

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