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Enhancer Fracking

Check out our newest collaborative paper with the Stern and Crocker labs, where a CRM was randomly mutagenized to death and the results analyzed in vivo using a high-throughput robotics platform.

Fuqua, T., Jordan, J., van Breugel, M.E. et al. Dense and pleiotropic regulatory information in a developmental enhancer. Nature (2020). https://doi.org/10.1038/s41586-020-2816-5

This thread, written by the first author, explains it super well.

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