For many of our projects, we generate new tools for the in vivo manipulation and characterization of gene function and expression.

For example:

Scarless engineering of the Drosophila genome near any site-specific integration site. Feng S, Lu S, Grueber WB, Mann RS. Genetics. 2021 Mar 31;217(3):iyab012. doi: 10.1093/genetics/iyab012. PMID: 33772309

Genome engineering: Voutev and Mann, 2018

Fly walking: Mendes et al., 2013

DNA binding specificity: Riley et al., 2014

Transcription factor binding specificity: Rastogi et al., 2018