For many of our projects, we generate new tools for the in vivo manipulation and characterization of gene function and expression.
For example:
Scarless engineering of the Drosophila genome near any site-specific integration site. Feng S, Lu S, Grueber WB, Mann RS. Genetics. 2021 Mar 31;217(3):iyab012. doi: 10.1093/genetics/iyab012. PMID: 33772309
Genome engineering: Voutev and Mann, 2018
Fly walking: Mendes et al., 2013
DNA binding specificity: Riley et al., 2014
Transcription factor binding specificity: Rastogi et al., 2018