Ryan Edmund Loker

Postdoc

Publications from PhD work:

1: Requena D, Álvarez JA, Gabilondo H, Loker R, Mann RS, Estella C. Origins and
Specification of the Drosophila Wing. Curr Biol. 2017 Dec
18;27(24):3826-3836.e5. doi: 10.1016/j.cub.2017.11.023. Epub 2017 Dec 7. PMID:
29225023; PMCID: PMC5757315.

2: Loker R, Sanner JE, Mann RS. Cell-type-specific Hox regulatory strategies
orchestrate tissue identity. Curr Biol. 2021 Jul 31:S0960-9822(21)00985-4. doi:
10.1016/j.cub.2021.07.030. Epub ahead of print. PMID: 34358443.

3: Diaz-de-la-Loza MD, Loker R, Mann RS, Thompson BJ. Control of tissue
morphogenesis by the HOX gene <i>Ultrabithorax</i>. Development. 2020 Mar
2;147(5):dev184564. doi: 10.1242/dev.184564. PMID: 32122911; PMCID: PMC7063672.

4: Kribelbauer JF, Loker RE, Feng S, Rastogi C, Abe N, Rube HT, Bussemaker HJ,
Mann RS. Context-Dependent Gene Regulation by Homeodomain Transcription Factor
Complexes Revealed by Shape-Readout Deficient Proteins. Mol Cell. 2020 Apr
2;78(1):152-167.e11. doi: 10.1016/j.molcel.2020.01.027. Epub 2020 Feb 12. PMID:
32053778; PMCID: PMC7197192.

5: Delker RK, Ranade V, Loker R, Voutev R, Mann RS. Low affinity binding sites
in an activating CRM mediate negative autoregulation of the Drosophila Hox gene
Ultrabithorax. PLoS Genet. 2019 Oct 7;15(10):e1008444. doi:
10.1371/journal.pgen.1008444. PMID: 31589607; PMCID: PMC6797233.

6: Rastogi C, Rube HT, Kribelbauer JF, Crocker J, Loker RE, Martini GD, Laptenko
O, Freed-Pastor WA, Prives C, Stern DL, Mann RS, Bussemaker HJ. Accurate and
sensitive quantification of protein-DNA binding affinity. Proc Natl Acad Sci U S
A. 2018 Apr 17;115(16):E3692-E3701. doi: 10.1073/pnas.1714376115. Epub 2018 Apr
2. PMID: 29610332; PMCID: PMC5910815.